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Released: 23-May-2024 2:00 PM EDT
Sequencing of the developing human brain uncovers hundreds of thousands of new gene transcripts
University of California, Los Angeles (UCLA), Health Sciences

Using new sequencing technologies, UCLA and University of Pennsylvania researchers uncovered 214,516 unique isoforms in the developing neocortex 鈥 over 70% of which have not been previously studied.

Released: 23-May-2024 9:05 AM EDT
Ohalo鈩 Announces the Discovery of Boosted Breeding鈩
Ohalo Genetics, Inc

Ohalo鈩 announced today the discovery of Boosted Breeding鈩, an entirely new plant breeding technology that will revolutionize agriculture and sustainably improve crop productivity.

日本无码: 5-aminolevulinic acid: enhancing tomato resilience against cold stress
Released: 23-May-2024 8:05 AM EDT
5-aminolevulinic acid: enhancing tomato resilience against cold stress
Chinese Academy of Sciences

Cold stress significantly hampers tomato growth and yield. Recent research reveals that 5-aminolevulinic acid (ALA) enhances cold tolerance in tomatoes by regulating the SlMYB4/SlMYB88-SlGSTU43 gene module. This discovery opens new avenues for genetic engineering to develop cold-resistant tomato varieties, potentially ensuring better crop resilience and productivity under low-temperature conditions.

日本无码: PMAT: a new tool for efficient assembly of plant mitochondrial genomes
Released: 23-May-2024 8:05 AM EDT
PMAT: a new tool for efficient assembly of plant mitochondrial genomes
Chinese Academy of Sciences

A new assembly toolkit, an efficient assembly toolkit (PMAT), is set to revolutionize the study of plant mitochondrial genomes (mitogenomes), offering an unprecedented approach to understanding plant evolution and cytoplasmic male sterile line breeding. This tool stands to overcome significant challenges in the complete assembly of plant mitogenomes, a task previously hindered by complex recombination events and horizontal gene transfers.

日本无码: A New Gene-Editing System Tackles Complex Diseases
Released: 21-May-2024 11:00 AM EDT
A New Gene-Editing System Tackles Complex Diseases
University of California San Diego

Current methods to model or correct mutations in live cells are inefficient, especially when multiplexing 鈥 installing multiple point mutations simultaneously across the genome. Researchers from the UC San Diego have developed new, efficient genome editing tools called multiplexed orthogonal base editors (MOBEs) to install multiple point mutations at once.

日本无码: Peach Perfection: Advanced Gene Networks Reveal Fruit Traits
Released: 19-May-2024 10:05 AM EDT
Peach Perfection: Advanced Gene Networks Reveal Fruit Traits
Chinese Academy of Sciences

A study has tapped into the peach genome, creating large-scale gene coexpression networks (GCNs) that predict gene functions and streamline the peach breeding process. This innovative approach addresses the complex task of identifying genes linked to desirable breeding traits in peaches.

日本无码: Sweet trade-offs: unraveling the genetic puzzle of strawberry flavor and yield
Released: 18-May-2024 8:05 AM EDT
Sweet trade-offs: unraveling the genetic puzzle of strawberry flavor and yield
Chinese Academy of Sciences

A recent study has unlocked the genetic secrets behind the sweetness of strawberries, a key factor in consumer preference. The research identifies key genetic markers that influence both the sugar content and yield of strawberries, offering a significant step forward in the breeding of sweeter, more productive varieties.

日本无码: Unlocking the genetic blueprint of apples: shape and size traits unveiled
Released: 18-May-2024 7:05 AM EDT
Unlocking the genetic blueprint of apples: shape and size traits unveiled
Chinese Academy of Sciences

New genomic insights from researchers unveil critical genes influencing apple fruit size and shape. Through a comprehensive genome-wide association study, the study identifies several genetic markers linked to these traits, offering potential for enhanced breeding strategies.

Released: 16-May-2024 1:05 PM EDT
Rutgers Health Researchers Profile Clinical, Gene and Protein Changes in 鈥楤rain Fog鈥 From Long COVID
Rutgers University-New Brunswick

Scientists examined cognitive impairment and recovery time in patients following COVID-19 infection.

日本无码: Media Tip: Getting genetic with it
Released: 16-May-2024 10:05 AM EDT
Media Tip: Getting genetic with it
Argonne National Laboratory

From lemur poop to good old human poop, our waste has a story to tell. The U.S. Department of Energy鈥檚 (DOE) Argonne National Laboratory鈥檚 Environmental Sample Preparation and Sequencing Facility (ESPSF) has the tools and technology to get to the bottom of genetic mysteries from the natural world. Facility Manager Sarah Owens can help shed light on the quirkier side of genetics.

   
Released: 15-May-2024 7:05 AM EDT
Foundation Fighting Blindness Partners with Prevention Genetics and Informed DNA to Advance My Retina Tracker庐 Genetic Testing Program
Foundation Fighting Blindness

The Foundation Fighting Blindness, the driving force in the global development of treatments and cures for blinding diseases, announces today its partnership with PreventionGenetics, a part of Exact Sciences, as its new genetic laboratory partner for the My Retina Tracker Genetic Testing Program.

   
13-May-2024 8:05 AM EDT
Study Reveals Mixed Public Opinion on Polygenic Embryo Screening for IVF
Harvard Medical School

Survey reveals nearly three-quarters of U.S. adults support using emerging technology to screen embryos during IVF for risk of developing certain health conditions or traits that arise from more than one gene. Only about one-third of respondents approved of using the technology to predict traits unrelated to disease. Nearly all expressed concerns about potential negative outcomes for individuals or society. Findings underscore need for public education about benefits, limitations, ethical hazards of polygenic risk scores for embryos.

日本无码: High genetic diversity discovered in South African leopards
Released: 13-May-2024 9:05 PM EDT
High genetic diversity discovered in South African leopards
University of Adelaide

Researchers say the discovery of very high genetic diversity in leopards found in the Highveld region of South Africa has increased the need for conservation efforts to protect leopards in the country.

日本无码: Mount Sinai Study Identifies Genetic Link Between Inflammatory Bowel Disease and Parkinson鈥檚 Disease
13-May-2024 12:05 PM EDT
Mount Sinai Study Identifies Genetic Link Between Inflammatory Bowel Disease and Parkinson鈥檚 Disease
Mount Sinai Health System

Researchers at the Icahn School of Medicine at Mount Sinai have made a significant discovery, identifying genetic connections between inflammatory bowel disease (IBD) and Parkinson鈥檚 disease (PD). Published in Genome Medicine on May 13, their study highlights the potential for joint therapeutic strategies to target these two challenging disorders.

Released: 13-May-2024 3:05 PM EDT
Herpes cure with gene editing makes progress in laboratory studies
Fred Hutchinson Cancer Center

Researchers at Fred Hutch Cancer Center have found in pre-clinical studies that an experimental gene therapy for genital and oral herpes removed 90% or more of the infection and suppressed how much virus can be released from an infected individual, which suggests that the therapy would also reduce the spread of the virus.

日本无码: Turning to Artificial Intelligence to Disentangle the Exposome
Released: 13-May-2024 12:15 PM EDT
Turning to Artificial Intelligence to Disentangle the Exposome
Harvard Medical School

Understanding the human exposome 鈥 a person鈥檚 myriad health exposures over a lifetime 鈥 can reveal unknowns about diseases not explained fully by our DNA. Artificial intelligence will be indispensable in efforts to understand the role of biology and environment in disease and health.

日本无码: Machine learning sheds light on gene transcription
Released: 13-May-2024 12:05 PM EDT
Machine learning sheds light on gene transcription
UT Southwestern Medical Center

A team led by researchers at UT Southwestern Medical Center developed deep learning models to identify a simple set of rules that govern the activity of promoters 鈥 regions of DNA that initiate the process by which genes produce proteins. Their findings, published in Science, could lead to a better understanding of how promoters contribute to gene regulation in health and disease.

日本无码: New Insight Into Genesis of Spina Bifida
Released: 8-May-2024 1:05 PM EDT
New Insight Into Genesis of Spina Bifida
University of California San Diego

Spina bifida is the most common structural disorder of the human nervous system. The causes are largely unknown, but University of California San Diego researchers led a study that points to a link involving a chromosomal microdeletion 鈥 and also underscores the value of folic acid as a preventive measure.

Released: 8-May-2024 11:05 AM EDT
Uniformed Services University Contributes to Groundbreaking Global Study on Multiple System Atrophy
Uniformed Services University of the Health Sciences (USU)

In a groundbreaking study published May 2, 2024 in Neuron, researchers have identified four new genetic risk factors for multiple system atrophy (MSA), shedding light on this poorly understood disorder.

Released: 7-May-2024 11:05 AM EDT
New genetic mutation identified for congenital thyroid condition
University of Chicago Medical Center

Research led by UChicago uncovers a genetic mutation that can lead to a rare form of thyroid abnormality.

日本无码: Game-changer in cancer science: how TP53gene loss drives gastric cancer evolution
Released: 7-May-2024 10:05 AM EDT
Game-changer in cancer science: how TP53gene loss drives gastric cancer evolution
Chinese Academy of Sciences

鈥淭he independent research groups, led by Prof. Scott W. Lowe and Christina Curtis,respectively, have uncovered a similar definitive pathway in the progression of gastric cancer (GC) initiated with loss of the TP53 gene, representing a milstone in understanding the early stages of this deadly disease鈥. Dr. Zhaocai Zhou, head of a GC laboratory from Fudan University, stated.

   
Released: 6-May-2024 12:05 PM EDT
Using Advanced Genetic Techniques, Scientists Create Mice With Traits of Tourette Disorder
Rutgers University-New Brunswick

In research that may be a step forward toward finding personalized treatments for Tourette disorder, scientists at Rutgers University鈥揘ew Brunswick have bred mice that exhibit some of the same behaviors and brain abnormalities seen in humans with the disorder. As reported in the Proceedings of the National Academy of Sciences, the researchers, using a technique known as CRISPR/Cas9 DNA editing, inserted the same genetic mutations found in humans with Tourette disorder into the corresponding genes in mouse embryos.

Released: 6-May-2024 9:00 AM EDT
Penn Medicine at the American Society of Gene and Cell Therapy 27th Annual Meeting
Perelman School of Medicine at the University of Pennsylvania

Researchers from the Gene Therapy Program (GTP) at the Perelman School of Medicine at the University of Pennsylvania will present ten research abstracts, two invited talks, and a workshop presentation highlighting their translational science and discovery research on gene therapy, gene editing, and adeno-associated virus (AAV) vector technology at the American Society of Cell and Gene Therapy (ASGCT) 27th Annual Meeting on May 7 - 11, 2024 in Baltimore, Maryland.

30-Apr-2024 10:05 AM EDT
Survey of U.S. Parents Highlights Need for More Awareness About Newborn Screening, Cystic Fibrosis and What to Do if Results are Abnormal
Ann and Robert H. Lurie Children's Hospital of Chicago

A national survey led by Ann & Robert H. Lurie Children鈥檚 Hospital of Chicago found that parents have insufficient knowledge of newborn screening in general and of cystic fibrosis (CF) in particular.

Released: 3-May-2024 6:05 AM EDT
A Revolution In Gene Therapy Is Unfolding, Bringing Hope for Vision Loss
American Macular Degeneration Foundation (AMDF)

A new approach to gene therapy resets cell homeostasis. Clinical trials to treat the retinal disorders Retinitis Pigmentosa, Stargardt's, and Geographic Atrophy (late dry macular degeneration) are underway and showing promise.

Released: 3-May-2024 2:05 AM EDT
Genetics, not lack of oxygen, causes cerebral palsy in quarter of cases
University of Adelaide

The world鈥檚 largest study of cerebral palsy (CP) genetics has discovered genetic defects are most likely responsible for more than a quarter of cases in Chinese children, rather than a lack of oxygen at birth as previously thought.

     
日本无码: Revealed: how cancer cells harness energy to drive disease progression
Released: 2-May-2024 7:05 AM EDT
Revealed: how cancer cells harness energy to drive disease progression
Chinese Academy of Sciences

Researchers have revealed crucial insights into how the Warburg effect causes the dedifferentiation of cancer cells through epigenetic reprogramming. This discovery potentially opens up new avenues for cancer treatments that target cellular metabolism.

日本无码: Researchers Discover Key Functions of Therapeutically Promising Jumbo Viruses
Released: 2-May-2024 12:05 AM EDT
Researchers Discover Key Functions of Therapeutically Promising Jumbo Viruses
University of California San Diego

Viruses known as 鈥渏umbo鈥 phages are seen as a potential tool against deadly bacterial infections. But scientists must first decipher the extraordinary makeup of these mysterious viruses. Researchers have now uncovered a key piece of jumbo phage development that helps them counter bacteria.

29-Apr-2024 1:05 PM EDT
CHOP Researchers Identify Causal Genetic Variant Linked to Common Childhood Obesity
Children's Hospital of Philadelphia

Researchers have identified a causal genetic variant strongly associated with childhood obesity. The study provides new insight into the importance of the hypothalamus of the brain and its role in common childhood obesity and the target gene may serve as a druggable target for future therapeutic interventions.

日本无码: An electrifying discovery may help doctors deliver more effective gene therapies
Released: 30-Apr-2024 2:30 PM EDT
An electrifying discovery may help doctors deliver more effective gene therapies
University of Wisconsin鈥揗adison

In an effort to improve delivery of costly medical treatments, a team of researchers in electrical engineering at the University of Wisconsin鈥揗adison has developed a stimulating method that could make the human body more receptive to certain gene therapies.

日本无码: New gene signature could transform immunotherapy for gastrointestinal cancers
Released: 30-Apr-2024 11:05 AM EDT
New gene signature could transform immunotherapy for gastrointestinal cancers
Chinese Academy of Sciences

A recent study in gastrointestinal (GI) cancer research reveals a promising advancement in predicting patient responses to immune checkpoint inhibitor (ICI) therapy. The newly developed DNA damage response-related immune activation (DRIA) signature could serve as a groundbreaking biomarker, providing valuable guidance for ICI therapy decisions.

日本无码: Unlocking the Genetic Mysteries Behind Plant Adaptation: New Insights into the Evolution of a Water-Saving Trait in the Pineapple Family (Bromeliaceae)
29-Apr-2024 7:00 AM EDT
Unlocking the Genetic Mysteries Behind Plant Adaptation: New Insights into the Evolution of a Water-Saving Trait in the Pineapple Family (Bromeliaceae)
University of Vienna

Researchers at the University of Vienna, along with collaborators from France, Germany, Switzerland and the USA, have achieved a major breakthrough in understanding how genetic drivers influence the evolution of a specific photosynthesis mechanism in Tillandsia (air plants). This sheds light on the complex actions that cause plant adaptation and ecological diversity. The results of their study are now published in Plant Cell.

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This news release is embargoed until 30-Apr-2024 7:00 AM EDT Released to reporters: 26-Apr-2024 3:15 PM EDT

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日本无码: Iowa State researchers identify genes linked to rice resiliency
Released: 29-Apr-2024 11:05 AM EDT
Iowa State researchers identify genes linked to rice resiliency
Iowa State University

Researchers at Iowa State University have identified two genes that can help rice defend itself against diseases, including the devastating fungal blast pathogen that regularly causes significant losses of rice production worldwide.

日本无码: After 25 Years, Researchers Uncover Genetic Cause of Rare Neurological Disease
25-Apr-2024 5:00 AM EDT
After 25 Years, Researchers Uncover Genetic Cause of Rare Neurological Disease
University of Utah Health

Spinocerebellar ataxia 4 is a devastating progressive movement disorder. A multinational study has now conclusively identified the genetic difference that causes the disease, bringing answers to families and opening the door to future treatments.

日本无码: Automated machine learning robot unlocks new potential for genetics research
Released: 26-Apr-2024 7:00 AM EDT
Automated machine learning robot unlocks new potential for genetics research
University of Minnesota College of Science and Engineering

University of Minnesota Twin Cities researchers have constructed a robot that uses machine learning to fully automate a complicated microinjection process used in genetic research.

日本无码: Genetic variations may predispose people to Parkinson鈥檚 disease following long-term pesticide exposure, study finds
22-Apr-2024 3:05 PM EDT
Genetic variations may predispose people to Parkinson鈥檚 disease following long-term pesticide exposure, study finds
University of California, Los Angeles (UCLA), Health Sciences

A new UCLA Health study found certain genetic variants could help explain how long-term pesticide exposure could increase the risk of Parkinson鈥檚 disease.

日本无码: Revolutionizing Sweetpotato Genetics: A Comprehensive Update to the 'Taizhong 6' Genome Annotation
Released: 25-Apr-2024 12:05 AM EDT
Revolutionizing Sweetpotato Genetics: A Comprehensive Update to the 'Taizhong 6' Genome Annotation
Chinese Academy of Sciences

A research team has substantially enhanced the annotation of the sweetpotato genome 'Taizhong 6', introducing a more comprehensive and detailed version, v1.0.a2.

24-Apr-2024 2:05 PM EDT
Researchers Publish Final Results of Key Clinical Trial for Gene Therapy for Sickle Cell Disease
Children's Hospital of Philadelphia

An international consortium published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).

日本无码: Newly discovered alteration of brain network condition could possibly predict extremely painful vaso-occlusive crisis in patients with sickle cell disease
Released: 24-Apr-2024 1:05 PM EDT
Newly discovered alteration of brain network condition could possibly predict extremely painful vaso-occlusive crisis in patients with sickle cell disease
Indiana University

A new study led by Indiana University School of Medicine researchers found a brain network condition called 鈥渆xplosive synchronization鈥 could be the cause of extreme pain crises in people with sickle cell disease.

Released: 24-Apr-2024 12:00 PM EDT
MD Anderson Research Highlights for April 24, 2024
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center鈥檚 Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson鈥檚 world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

   
日本无码: The first chromosome-level reference genomes of the ornamental banana and pink banana
Released: 24-Apr-2024 11:05 AM EDT
The first chromosome-level reference genomes of the ornamental banana and pink banana
Chinese Academy of Sciences

The genus Musa, encompassing approximately 70 herbaceous species, is predominantly found in the tropical and subtropical regions of Asia and Oceania.

日本无码: Unveiling the Genetic Blueprint of Safflower: A Leap Forward in Crop Breeding and Biomedical Research
Released: 24-Apr-2024 11:05 AM EDT
Unveiling the Genetic Blueprint of Safflower: A Leap Forward in Crop Breeding and Biomedical Research
Chinese Academy of Sciences

A research team completes a high-quality chromosome-scale assembly of the 'Chuanhonghua 1' safflower genome.

Released: 24-Apr-2024 11:05 AM EDT
UC Irvine to lead study of how DNA genetic variations might influence nicotine addiction
University of California, Irvine

A three-year, $1.19 million grant from the Tobacco-Related Disease Research Program will allow University of California, Irvine researchers to explore how specific sections of DNA might influence nicotine addiction. Deeper insights into these neurological processes may lead to more effective prevention and treatment strategies for cigarette smoking and vaping habits.

Released: 24-Apr-2024 10:05 AM EDT
Global consortium to study Pick's disease, rare form of early-onset dementia
Mayo Clinic

Pick's disease, a neurodegenerative disease of unknown genetic origin, is a rare type of frontotemporal dementia that affects people under the age of 65.



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