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日本无码: SLAS Technology Presents: Advances in Synthetic Biology
Released: 23-May-2024 11:00 AM EDT
SLAS Technology Presents: Advances in Synthetic Biology
SLAS

Volume 29, Issue 2 of SLAS Technology, includes three original research articles covering skin cutaneous melanoma, glycan-bead coupling and acoustic ejection mass spectrometry, and eight articles from the Advances in Synthetic Biology Special Issue.

日本无码: 5-aminolevulinic acid: enhancing tomato resilience against cold stress
Released: 23-May-2024 8:05 AM EDT
5-aminolevulinic acid: enhancing tomato resilience against cold stress
Chinese Academy of Sciences

Cold stress significantly hampers tomato growth and yield. Recent research reveals that 5-aminolevulinic acid (ALA) enhances cold tolerance in tomatoes by regulating the SlMYB4/SlMYB88-SlGSTU43 gene module. This discovery opens new avenues for genetic engineering to develop cold-resistant tomato varieties, potentially ensuring better crop resilience and productivity under low-temperature conditions.

日本无码: PMAT: a new tool for efficient assembly of plant mitochondrial genomes
Released: 23-May-2024 8:05 AM EDT
PMAT: a new tool for efficient assembly of plant mitochondrial genomes
Chinese Academy of Sciences

A new assembly toolkit, an efficient assembly toolkit (PMAT), is set to revolutionize the study of plant mitochondrial genomes (mitogenomes), offering an unprecedented approach to understanding plant evolution and cytoplasmic male sterile line breeding. This tool stands to overcome significant challenges in the complete assembly of plant mitogenomes, a task previously hindered by complex recombination events and horizontal gene transfers.

日本无码:Video Embedded fresh-hope-for-chronic-wounds
VIDEO
Released: 22-May-2024 4:05 PM EDT
Fresh hope for chronic wounds
University of Delaware

The U.S. Food and Drug Administration recently approved two new wound management products that include patented hydrogels invented by University of Delaware researchers. The unique UD hydrogel materials self-assemble to form a 3D matrix compatible with living cells.

日本无码: A New Gene-Editing System Tackles Complex Diseases
Released: 21-May-2024 11:00 AM EDT
A New Gene-Editing System Tackles Complex Diseases
University of California San Diego

Current methods to model or correct mutations in live cells are inefficient, especially when multiplexing 鈥 installing multiple point mutations simultaneously across the genome. Researchers from the UC San Diego have developed new, efficient genome editing tools called multiplexed orthogonal base editors (MOBEs) to install multiple point mutations at once.

日本无码: Melon Flavor Decoded: The Genetic Keys to Aromatic Diversity
Released: 20-May-2024 10:05 AM EDT
Melon Flavor Decoded: The Genetic Keys to Aromatic Diversity
Chinese Academy of Sciences

This study investigates the genetic regulation of volatile production in melons, identifying over 1000 quantitative trait loci (QTLs) affecting aroma and ripening. Key findings highlight specific chromosomes that influence ester and aldehyde levels, contributing to unique aromas in climacteric and non-climacteric melons, aiding breeding programs aimed at enhancing fruit quality.

日本无码: Revolutionizing Plastic-Greenhouse Agriculture: A Novel Soil Profile Design for Global Sustainability and Enhanced Crop Production
Released: 20-May-2024 5:05 AM EDT
Revolutionizing Plastic-Greenhouse Agriculture: A Novel Soil Profile Design for Global Sustainability and Enhanced Crop Production
Chinese Academy of Sciences

A research team has developed a novel conceptual framework for designing plastic-greenhouse soil profiles that cater to the needs of smallholder farmers.

日本无码: Exploring the Multifaceted Role of MicroRNA156 in Horticultural Plants: A Review of Its Regulatory Impact and Biotechnological Potential
Released: 20-May-2024 5:05 AM EDT
Exploring the Multifaceted Role of MicroRNA156 in Horticultural Plants: A Review of Its Regulatory Impact and Biotechnological Potential
Chinese Academy of Sciences

A research team has reviewed the role of MicroRNA156 (miR156) in horticultural plants, uncovering its significant influence on a variety of biological processes such as vegetative growth, floral induction, and stress response.

日本无码: Unveiling the Genetic Interplay in Impatiens Downy Mildew: A Transcriptome-Based Approach to Enhancing Disease Resistance
Released: 20-May-2024 4:05 AM EDT
Unveiling the Genetic Interplay in Impatiens Downy Mildew: A Transcriptome-Based Approach to Enhancing Disease Resistance
Chinese Academy of Sciences

A research team has meticulously analyzed the transcriptional response of Impatiens walleriana to Plasmopara obducens infection, revealing between 3,000 and 4,500 differentially expressed transcripts at various stages of the disease.

日本无码: Peach Perfection: Advanced Gene Networks Reveal Fruit Traits
Released: 19-May-2024 10:05 AM EDT
Peach Perfection: Advanced Gene Networks Reveal Fruit Traits
Chinese Academy of Sciences

A study has tapped into the peach genome, creating large-scale gene coexpression networks (GCNs) that predict gene functions and streamline the peach breeding process. This innovative approach addresses the complex task of identifying genes linked to desirable breeding traits in peaches.

日本无码: Warding off winter woes: advanced AI model shields grapevines from frost
Released: 19-May-2024 10:05 AM EDT
Warding off winter woes: advanced AI model shields grapevines from frost
Chinese Academy of Sciences

A study introduces an automated machine learning (Auto-ML) model that predicts the freezing tolerance of grapevines in real-time, a critical advancement for sustainable grape production in cooler climates. This model leverages hourly temperature data and varietal specifics to forecast cold hardiness, a significant step towards precision viticulture.

日本无码: Strawberry fields fortified: new genetic insights combat devastating soilborne disease
Released: 19-May-2024 10:05 AM EDT
Strawberry fields fortified: new genetic insights combat devastating soilborne disease
Chinese Academy of Sciences

Recent research has unveiled the genetic foundations of resistance in strawberries to Macrophomina, a formidable soilborne disease. Employing cutting-edge breeding strategies and genomic analysis, scientists have pinpointed crucial genetic loci responsible for resistance, heralding a new era of more robust strawberry varieties.

日本无码: Sweet trade-offs: unraveling the genetic puzzle of strawberry flavor and yield
Released: 18-May-2024 8:05 AM EDT
Sweet trade-offs: unraveling the genetic puzzle of strawberry flavor and yield
Chinese Academy of Sciences

A recent study has unlocked the genetic secrets behind the sweetness of strawberries, a key factor in consumer preference. The research identifies key genetic markers that influence both the sugar content and yield of strawberries, offering a significant step forward in the breeding of sweeter, more productive varieties.

日本无码: Unlocking the genetic blueprint of apples: shape and size traits unveiled
Released: 18-May-2024 7:05 AM EDT
Unlocking the genetic blueprint of apples: shape and size traits unveiled
Chinese Academy of Sciences

New genomic insights from researchers unveil critical genes influencing apple fruit size and shape. Through a comprehensive genome-wide association study, the study identifies several genetic markers linked to these traits, offering potential for enhanced breeding strategies.

日本无码: Melon's molecular armor: new insights into crop protection
Released: 18-May-2024 6:05 AM EDT
Melon's molecular armor: new insights into crop protection
Chinese Academy of Sciences

A new study has uncovered a genetic treasure trove within the melon genome that could revolutionize the plant's defense against pests and diseases. Researchers have identified a cluster of genes that bestow resistance to both powdery mildew and aphids, two of the most devastating threats to melon crops worldwide.

日本无码: A new chapter in grape cultivation: non-transgenic plant regeneration technology
Released: 18-May-2024 6:05 AM EDT
A new chapter in grape cultivation: non-transgenic plant regeneration technology
Chinese Academy of Sciences

Biotechnological innovation meets horticulture as researchers unveil a cutting-edge genome editing protocol for grapes. This novel technique, integrating protoplast culture with CRISPR-Cas9, facilitates the regeneration of non-chimeric, transgene-free plants across a spectrum of grape varieties.

日本无码: Repeat COVID-19 vaccinations elicit antibodies that neutralize variants, other viruses
Released: 17-May-2024 1:05 PM EDT
Repeat COVID-19 vaccinations elicit antibodies that neutralize variants, other viruses
Washington University in St. Louis

A study by researchers at Washington University School of Medicine in St. Louis has found that repeat vaccination with updated versions of the COVID-19 vaccine promotes the development of antibodies that neutralize a wide range of variants of the virus that causes COVID-19, as well as related coronaviruses.

日本无码: Fast track to food safety: new test spots seafood pathogen in 30 minutes
Released: 16-May-2024 10:05 AM EDT
Fast track to food safety: new test spots seafood pathogen in 30 minutes
Chinese Academy of Sciences

Researchers have developed a groundbreaking point-of-care detection method for Vibrio parahaemolyticus, a bacterium responsible for a significant number of foodborne illnesses. The new platform, leveraging recombinant polymerase amplification (RPA) and the CRISPR/Cas12a system combined with an immunochromatographic test strip (ICS), offers a low-cost, simple, and visually intuitive solution for the rapid detection of this pathogen in seafood.

   
日本无码: Media Tip: Getting genetic with it
Released: 16-May-2024 10:05 AM EDT
Media Tip: Getting genetic with it
Argonne National Laboratory

From lemur poop to good old human poop, our waste has a story to tell. The U.S. Department of Energy鈥檚 (DOE) Argonne National Laboratory鈥檚 Environmental Sample Preparation and Sequencing Facility (ESPSF) has the tools and technology to get to the bottom of genetic mysteries from the natural world. Facility Manager Sarah Owens can help shed light on the quirkier side of genetics.

   
Released: 16-May-2024 8:05 AM EDT
Gene therapy relieves back pain, repairs damaged disc in mice
Ohio State University

Disc-related back pain may one day meet its therapeutic match: gene therapy delivered by naturally derived nanocarriers that, a new study shows, repairs damaged discs in the spine and lowers pain symptoms in mice.

   
日本无码: emeritus-11-d0060704-studier-hr.jpeg
Released: 14-May-2024 9:05 AM EDT
Brookhaven Lab Biophysicist F. William Studier Awarded Merkin Prize in Biomedical Technology
Brookhaven National Laboratory

F. William Studier, a senior biophysicist emeritus at the U.S. Department of Energy's 'Brookhaven National Laboratory, has won the 2024 Richard N. Merkin Prize in Biomedical Technology for his development in the 1980s of an efficient, scalable method of producing RNA and proteins in the laboratory.

   
日本无码: Development of technology for producing bioplastics from agricultural and food byproducts by the World Institute of Kimchi
Released: 10-May-2024 9:00 AM EDT
Development of technology for producing bioplastics from agricultural and food byproducts by the World Institute of Kimchi
National Research Council of Science and Technology

Hae Choon Chang, President of the World Institute of Kimchi (WiKim) announced on April 22 that the institute has developed a 'bio-refactoring-based upcycling technology' that can convert cabbage byproducts discarded as waste during the food manufacturing process into biodegradable plastics.

Released: 9-May-2024 4:05 AM EDT
New DNA origami technique promises breakthroughs in medicine
University of Portsmouth

A new study led by the University of Portsmouth in England has developed an innovative method to customise and strengthen DNA origami structures, which could lead to advances in medicine, biotechnology, and beyond.

日本无码: Smart labs for bespoke synthesis of nanomaterials are emerging
Released: 7-May-2024 12:00 AM EDT
Smart labs for bespoke synthesis of nanomaterials are emerging
National Research Council of Science and Technology

The Korea Institute of Science and Technology (KIST) announced that Dr. Sang Soo, Han and Dr. Donghun, Kim of the Computational Science Research Center and Professor Kwan-Young Lee of the Department of Chemical Engineering and Biotechnology at Korea University (President Kim Dong-won) have developed a bespoke synthesis platform of nanomaterials using AI and robotics, called Smart Lab.

Released: 2-May-2024 9:05 PM EDT
Gene Expression and Bioinformatics Tools to Optimize Cancer Therapy
Sbarro Health Research Organization (SHRO)

In the field of biomedical research and genomics, the advancement of bioinformatics technologies and tools is opening new frontiers in the understanding of diseases and their diagnosis and treatment.

日本无码: Marriage of synthetic biology and 3D printing produces programmable living materials
26-Apr-2024 8:00 AM EDT
Marriage of synthetic biology and 3D printing produces programmable living materials
American Chemical Society (ACS)

Researchers report in ACS Central Science that they have 3D printed a bioink containing plant cells that were then genetically modified, producing programmable materials. Applications could someday include biomanufacturing and sustainable construction.

Not for public release

This news release is embargoed until 30-Apr-2024 7:00 AM EDT Released to reporters: 26-Apr-2024 8:10 AM EDT

A reporter's PressPass is required to access this story until the embargo expires on 30-Apr-2024 7:00 AM EDT The 日本无码 PressPass gives verified journalists access to embargoed stories. Please log in to complete a presspass application. If you have not yet registered, please Register. When you fill out the registration form, please identify yourself as a reporter in order to advance to the presspass application form.

Not for public release

This news release is embargoed until 30-Apr-2024 7:00 AM EDT Released to reporters: 26-Apr-2024 3:15 PM EDT

A reporter's PressPass is required to access this story until the embargo expires on 30-Apr-2024 7:00 AM EDT The 日本无码 PressPass gives verified journalists access to embargoed stories. Please log in to complete a presspass application. If you have not yet registered, please Register. When you fill out the registration form, please identify yourself as a reporter in order to advance to the presspass application form.

日本无码:Video Embedded icahn-school-of-medicine-at-mount-sinai-names-miriam-merad-md-phd-as-dean-for-translational-research-and-therapeutic-innovation
VIDEO
29-Apr-2024 9:00 AM EDT
Icahn School of Medicine at Mount Sinai Names Miriam Merad, MD, PhD, as Dean for Translational Research and Therapeutic Innovation
Mount Sinai Health System

Miriam Merad, MD, PhD, a world-renowned immunologist, has been appointed Dean for Translational Research and Therapeutic Innovation of the Icahn School of Medicine at Mount Sinai. The appointment reaffirms Icahn Mount Sinai鈥檚 commitment to pioneering medical progress and catalyzing the rapid advancement of research innovation. Dr. Merad, the Mount Sinai Professor in Cancer Immunology, will also continue to serve as the founding Chair of the Department of Immunology and Immunotherapy, Director of the Marc and Jennifer Lipschultz Precision Immunology Institute, and Director of the Human Immune Monitoring Center. As Dean, Dr. Merad aims to elevate early clinical trials at Icahn Mount Sinai, streamline the clinical trial process, cultivate a culture of mechanistic clinical trials throughout the campus, and forge stronger partnerships with the pharmaceutical and biotech sectors.

Released: 26-Apr-2024 12:00 PM EDT
Interplay between mesenchymal stem cells and macrophages: Promoting bone tissue repair
World Journal of Stem Cells

The repair of bone tissue damage is a complex process that is well-orchestrated in time and space, a focus and difficulty in orthopedic treatment. In recent years, the success of mesenchymal stem cells (MSCs)-mediated bone repair in clinica

Released: 26-Apr-2024 12:00 PM EDT
Mesenchymal stem cells and their derived exosomes for the treatment of COVID-19
World Journal of Stem Cells

Coronavirus disease 2019 (COVID-19) is an acute respiratory infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 infection typically presents with fever and respiratory symptoms, which can progress to

Released: 26-Apr-2024 12:00 PM EDT
Biological scaffold as potential platforms for stem cells: Current development and applications in wound healing
World Journal of Stem Cells

Wound repair is a complex challenge for both clinical practitioners and researchers. Conventional approaches for wound repair have several limitations. Stem cell-based therapy has emerged as a novel strategy to address this issue, exhibitin

Released: 26-Apr-2024 12:00 PM EDT
Effects of high glucose and severe hypoxia on the biological behavior of mesenchymal stem cells at various passages
World Journal of Stem Cells

BACKGROUNDMesenchymal stem cells (MSCs) have been extensively studied for therapeutic potential, due to their regenerative and immunomodulatory properties. Serial passage and stress factors may affect the biological characteristics of MSCs,

Released: 26-Apr-2024 12:00 PM EDT
Gossypol acetic acid regulates leukemia stem cells by degrading LRPPRC via inhibiting IL-6/JAK1/STAT3 signaling or resulting mitochondrial dysfunction
World Journal of Stem Cells

BACKGROUNDLeukemia stem cells (LSCs) are found to be one of the main factors contributing to poor therapeutic effects in acute myeloid leukemia (AML), as they are protected by the bone marrow microenvironment (BMM) against conventional ther

Released: 26-Apr-2024 12:00 PM EDT
Expansion of human umbilical cord derived mesenchymal stem cells in regenerative medicine
World Journal of Stem Cells

BACKGROUNDStem cells are undifferentiated cells that possess the potential for self-renewal with the capacity to differentiate into multiple lineages. In humans, their limited numbers pose a challenge in fulfilling the necessary demands for

Released: 26-Apr-2024 12:00 PM EDT
Reveal more mechanisms of precondition mesenchymal stem cells inhibiting inflammation
World Journal of Stem Cells

Hypoxia can get more ability to inhibit inflammation. But how it impact on survival time of mesenchymal stem cells (MSCs) is confusing and how preconditioned MSCs inhibiting inflammation are partially known. Those issues decided the value o

Released: 26-Apr-2024 12:00 PM EDT
Unveiling the role of hypoxia-inducible factor 2alpha in osteoporosis: Implications for bone health
World Journal of Stem Cells

BACKGROUNDOsteoporosis (OP) has become a major public health problem worldwide. Most OP treatments are based on the inhibition of bone resorption, and it is necessary to identify additional treatments aimed at enhancing osteogenesis. In the

Released: 26-Apr-2024 12:00 PM EDT
Adipose-derived regenerative therapies for the treatment of knee osteoarthritis
World Journal of Stem Cells

Knee osteoarthritis is a degenerative condition with a significant disease burden and no disease-modifying therapy. Definitive treatment ultimately requires joint replacement. Therapies capable of regenerating cartilage could significantly

日本无码: Scientists Discover a New Signaling Pathway and Design a Novel Drug for Liver Fibrosis
Released: 25-Apr-2024 4:05 PM EDT
Scientists Discover a New Signaling Pathway and Design a Novel Drug for Liver Fibrosis
University of California San Diego

Scientists from the University of California San Diego discovered a novel signaling pathway in liver cells, leading to a treatment for fibrosis.

Released: 25-Apr-2024 11:05 AM EDT
Nanomaterial that mimics proteins could be basis for new neurodegenerative disease treatments
University of Wisconsin鈥揗adison

A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for treating Alzheimer鈥檚 and other neurodegenerative diseases. The nanomaterial alters the interaction between two key proteins in brain cells 鈥 with a potentially powerful therapeutic effect.

日本无码: Revolutionizing Mei (Prunus mume) Breeding: Genomic Insights into Ornamental and Cold Resistance Traits
Released: 25-Apr-2024 3:05 AM EDT
Revolutionizing Mei (Prunus mume) Breeding: Genomic Insights into Ornamental and Cold Resistance Traits
Chinese Academy of Sciences

A research team has provided an overview for understanding the genetic basis of ornamental and cold resistance traits in Mei (Prunus mume), a tree valued both for its ornamental and cultural significance in China.

日本无码: Factor Bioscience to Deliver Seven Presentations at the American Society of Gene & Cell Therapy (ASGCT) 27th Annual Meeting
Released: 23-Apr-2024 7:05 AM EDT
Factor Bioscience to Deliver Seven Presentations at the American Society of Gene & Cell Therapy (ASGCT) 27th Annual Meeting
Factor Bioscience

Factor Bioscience Inc., a Cambridge-based biotechnology company focused on developing mRNA and cell-engineering technologies, announced its participation in the American Society of Gene & Cell Therapy (ASGCT) 27th Annual Meeting to be held in Baltimore, MD from May 7-11, 2024.

Released: 26-Mar-2024 3:05 PM EDT
Biotechnology CEO and Inventor of SiriusXM Satellite Radio Martine Rothblatt to Deliver Graduation Address to the University of Maryland School of Medicine鈥檚 215th Graduating Class
University of Maryland School of Medicine

University of Maryland School of Medicine (UMSOM) Dean Mark T. Gladwin, MD, announced today that Martine Rothblatt PhD, JD, MBA, Chairperson and CEO of United Therapeutics, and inventor of SiriusXM Satellite Radio, will deliver the keynote address for this year鈥檚 graduating medical student class. The UMSOM MD graduation ceremony will take place at the Hippodrome Theatre on Thursday, May 16, 2024.

   
Released: 26-Mar-2024 12:00 PM EDT
Low-intensity pulsed ultrasound reduces alveolar bone resorption during orthodontic treatment via Lamin A/C-Yes-associated protein axis in stem cells
World Journal of Stem Cells

BACKGROUNDThe bone remodeling during orthodontic treatment for malocclusion often requires a long duration of around two to three years, which also may lead to some complications such as alveolar bone resorption or tooth root resorption. Lo

Released: 26-Mar-2024 12:00 PM EDT
O-linked 尾-N-acetylglucosaminylation may be a key regulatory factor in promoting osteogenic differentiation of bone marrow mesenchymal stromal cells
World Journal of Stem Cells

Cumulative evidence suggests that O-linked 尾-N-acetylglucosaminylation (O-GlcNAcylation) plays an important regulatory role in pathophysiological processes. Although the regulatory mechanisms of O-GlcNAcylation in tumors have been graduall

Released: 26-Mar-2024 12:00 PM EDT
Evaluation of genetic response of mesenchymal stem cells to nanosecond pulsed electric fields by whole transcriptome sequencing
World Journal of Stem Cells

BACKGROUNDMesenchymal stem cells (MSCs) modulated by various exogenous signals have been applied extensively in regenerative medicine research. Notably, nanosecond pulsed electric fields (nsPEFs), characterized by short duration and high st

Released: 26-Mar-2024 12:00 PM EDT
Long-term outcome of stem cell transplantation with and without anti-tumor necrotic factor therapy in perianal fistula with Crohn鈥檚 disease
World Journal of Stem Cells

BACKGROUNDStem cell transplantation is a promising therapeutic option for curing perianal fistula in Crohn鈥檚 disease (CD). Anti-tumor necrotic factor (TNF) therapy combined with drainage procedure is effective as well. However, previous s

Released: 26-Mar-2024 12:00 PM EDT
Understanding host-graft crosstalk for predicting the outcome of stem cell transplantation
World Journal of Stem Cells

Mesenchymal stromal cells (MSCs) hold great promise for tissue regeneration in debilitating disorders. Despite reported improvements, the short-term outcomes of MSC transplantation, which is possibly linked to poor cell survival, demand ext

Released: 26-Mar-2024 12:00 PM EDT
Self-assembly of differentiated dental pulp stem cells facilitates spheroid human dental organoid formation and prevascularization
World Journal of Stem Cells

BACKGROUNDThe self-assembly of solid organs from stem cells has the potential to greatly expand the applicability of regenerative medicine. Stem cells can self-organise into microsized organ units, partially modelling tissue function and re

Released: 26-Mar-2024 12:00 PM EDT
How mesenchymal stem cells transform into adipocytes: Overview of the current understanding of adipogenic differentiation
World Journal of Stem Cells

Mesenchymal stem cells (MSCs) are stem/progenitor cells capable of self-renewal and differentiation into osteoblasts, chondrocytes and adipocytes. The transformation of multipotent MSCs to adipocytes mainly involves two subsequent steps fro



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